Article
A genome-wide linkage scan provides evidence for both new and previously reported loci influencing common migraine.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Oct 2008
Ligthart Lannie, Nyholt Dale R, Hottenga Jouke-Jan, Distel Marijn A, Willemsen Gonneke, Boomsma Dorret I
Abstract excerpt
Latent class analysis was performed on migraine symptom data collected in a Dutch population sample (N = 12,210, 59% female) in order to obtain empirical groupings of individuals suffering from symptoms of migraine headache. Based on these heritable groupings (h(2) = 0.49, 95% CI: 0.41-0.57) individuals were classified as affected (migrainous headache) or unaffected. Genome-wide linkage analysis was performed...
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