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Article

Performance and scalability of discriminative metrics for comparative gene identification in 12 Drosophila genomes.

PLoS computational biology - 18 Apr 2008

Lin Michael F, Deoras Ameya N, Rasmussen Matthew D, Kellis Manolis

Abstract excerpt

Comparative genomics of multiple related species is a powerful methodology for the discovery of functional genomic elements, and its power should increase with the number of species compared. Here, we use 12 Drosophila genomes to study the power of comparative genomics metrics to distinguish between protein-coding and non-coding regions. First, we study the relative power of different comparative metrics and...

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PMID: 18421375
DOI: 10.1371/journal.pcbi.1000067
PMCID: PMC2291194

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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