Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DGINN, an automated and highly-flexible pipeline for the detection of genetic innovations on protein-coding genes.

Nucleic acids research - 9 Oct 2020

Picard Lea, Ganivet Quentin, Allatif Omran, Cimarelli Andrea, Guéguen Laurent, Etienne Lucie

Abstract excerpt

Adaptive evolution has shaped major biological processes. Finding the protein-coding genes and the sites that have been subjected to adaptation during evolutionary time is a major endeavor. However, very few methods fully automate the identification of positively selected genes, and widespread sources of genetic innovations such as gene duplication and recombination are absent from most pipelines. Here, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Databases, Genetic
Share to Evolution, Molecular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Primates

Share to Proteins

Share to Selection, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 32941639
DOI: 10.1093/nar/gkaa680
PMCID: PMC7544217

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DGINN, an automated and highly-flexible pipeline for the detection of genetic innovations on protein-coding genes.PMID 32941639Read ↗

Conservation motifs - a novel evolutionary-based classification of proteinsSemantic proximity Read ↗

Genome-wide detection of selection and other evolutionary forces.Semantic proximity Read ↗

A comparative genomics multitool for scientific discovery and conservation.Semantic proximity Read ↗

Mutations in disordered proteins as early indicators of nucleic acid changes triggering speciationSemantic proximity Read ↗

Functional innovation through new genes as a general evolutionary process.Semantic proximity Read ↗

Breaking Through Biology's Data Wall: Expanding the Known Tree of Life by Over 10x using a Global Biodiscovery PipelineSemantic proximity Read ↗

Structural variation, selection, and diversification of the NPIP gene family from the human pangenome.Semantic proximity Read ↗

An efficient and robust ABC approach to infer the rate and strength of adaptationSemantic proximity Read ↗

POTION: an end-to-end pipeline for positive Darwinian selection detection in genome-scale data through phylogenetic comparison of protein-coding genesSemantic proximity Read ↗

An efficient and robust ABC approach to infer the rate and strength of adaptation.Semantic proximity Read ↗

Performance and scalability of discriminative metrics for comparative gene identification in 12 Drosophila genomes.Semantic proximity Read ↗

TrioNsight: Building a meta-predictor to evaluate the clinical impact of TrioN-like Dbl-homology domain variantsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.