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Article

Molecular pathogenesis of T-cell leukaemia and lymphoma.

Nature reviews. Immunology - 1 May 2008

Aifantis Iannis, Raetz Elizabeth, Buonamici Silvia

Abstract excerpt

T-cell acute lymphoblastic leukaemia (T-ALL) is induced by the transformation of T-cell progenitors and mainly occurs in children and adolescents. Although treatment outcome in patients with T-ALL has improved in recent years, patients with relapsed disease continue to have a poor prognosis. It is therefore important to understand the molecular pathways that control both the induction of transformation and the...

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Identifiers

PMID: 18421304
DOI: 10.1038/nri2304

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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