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Article

High-grade Transformation of Low-grade B-cell Lymphoma: Pathology and Molecular Pathogenesis.

The American journal of surgical pathology - 1 Jan 2016

Agbay Rose Lou Marie C, Loghavi Sanam, Medeiros L Jeffrey, Khoury Joseph D

Abstract excerpt

Patients with low-grade (clinically indolent) lymphomas are at risk to undergo transformation to high-grade (clinically aggressive) lymphoma, although transformation only occurs in a subset of patients. When transformation occurs it is a critical event that determines the course of disease and is associated with unfavorable patient outcomes. Accurate detection of transformation, predictive biomarkers, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26658667
DOI: 10.1097/PAS.0000000000000561

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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