Article
Genetic and molecular analysis of the central and peripheral circadian clockwork of mice.
Cold Spring Harbor symposia on quantitative biology - 1 Jan 2007
Maywood E S, O'Neill J S, Reddy A B, Chesham J E, Prosser H M, Kyriacou C P, Godinho S I H, Nolan P M, Hastings M H
Abstract excerpt
A hierarchy of interacting, tissue-based clocks controls circadian physiology and behavior in mammals. Preeminent are the suprachiasmatic nuclei (SCN): central hypothalamic pacemakers synchronized to solar time via retinal afferents and in turn responsible for internal synchronization of other clocks present in major organ systems. The SCN and peripheral clocks share essentially the same cellular timing...
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