[Genetical conditioning of fluoroquinolone resistance mechanisms of clinical enterococcus faecalis strains. II. The mutations present in the qrdrs of gyrA, gyrB, parC and parE genes].

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[Genetical conditioning of fluoroquinolone resistance mechanisms of clinical enterococcus faecalis strains. II. The mutations present in the qrdrs of gyrA, gyrB, parC and parE genes].

Medycyna doswiadczalna i mikrobiologia - 1 Jan 2007

Piekarska Katarzyna, Jagielski Marek

Abstract excerpt

The analyze selected fluoroquinolone resistance mechanisms of clinical E. faecalis strains was presented. In the second part of the study of genetic polymorphisms and mutations in the QRDRs of gyrA, gyrB, parC and parE genes were analyzed. The MSSCP technique and DNA sequencing were used. The activity (MICs) of ciprofloxacin, sparfloxacin and moxifloxacin were determined against 180 tested strains. The MSSCP...

Topics

Amino Acid Substitution
Aza Compounds
Bacterial Proteins
Ciprofloxacin
DNA Gyrase
DNA Topoisomerase IV
DNA, Bacterial
Drug Resistance, Bacterial
Enterococcus faecalis
Fluoroquinolones

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genes, Bacterial

Microbial Sensitivity Tests

Moxifloxacin

Mutation

Polymerase Chain Reaction

Quinolines

Species Specificity

Source

Open in PubMed

Identifiers

PMID: 18416125

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-18416125-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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