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[Role of mutations in parC and gyrA in forming resistance of Mycoplasma hominis to fluoroquinolones].

Molekuliarnaia genetika, mikrobiologiia i virusologiia - 1 Jan 1999

Gushchin A E, Ladygina V G, Govorun V M

Abstract excerpt

The set of the laboratory strain M. hominis H-34 mutants resistant to fluoroquinolones (ciprofloxacin-Cfl, lomefloxacin-Lfl, ofloxacin-Ofl) was obtained by selection in broth medium. The mutation was found in the quinolone resistance-determining region (QRDR) of A subunit of topoisomerase IV gene (parC) and new mutations were found in QRDR of genes encoding the A subunit of DNA gyrase (gyrA) in M. hominis mutants...

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PMID: 10621934

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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[Role of mutations in parC and gyrA in forming resistance of Mycoplasma hominis to fluoroquinolones].PMID 10621934Read ↗

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Cloning and nucleotide sequence of the DNA gyrase (gyrA) gene from Mycoplasma hominis and characterization of quinolone-resistant mutants selected in vitro with trovafloxacin.Semantic proximity Read ↗

Mutations in the gyrA, parC, and parE genes associated with fluoroquinolone resistance in clinical isolates of Mycoplasma hominis.Semantic proximity Read ↗

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