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Article

[Resistance of Russian isolates of Neisseria gonorrhoeae to fluoroquinolones].

Molekuliarnaia genetika, mikrobiologiia i virusologiia - 1 Jan 2005

Vereshchagin V A, Il'una E N, Malakhova M V, Zubkov M M, Sidorenko S V, Kubanova A A, Govorun V M

Abstract excerpt

Fluoroquinolones still belong to the drugs of choice in the treatment of uncomplicated gonorrhea. At the same time, there have been more data on the spreading N. gonorrhoeae strains resistant to fluoroquinolones. A variety of mechanisms, like modification of the target of antibiotic's action (point mutations in genes gyrA and parC), a decreasing permeability of the bacterial cell membrane (amino-acid changes Por...

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PMID: 15790029

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