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Article

Functional significance of allelic variation at methuselah, an aging gene in Drosophila.

PloS one - 16 Apr 2008

Paaby Annalise B, Schmidt Paul S

Abstract excerpt

BACKGROUND: Longevity and age-specific patterns of mortality are complex traits that vary within and among taxa. Multiple candidate genes for aging have been identified in model systems by extended longevity mutant phenotypes, including the G-protein coupled receptor methuselah (mth) in D. melanogaster. These genes offer important insights into the mechanisms of lifespan determination and have been major targets...

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Identifiers

PMID: 18414670
DOI: 10.1371/journal.pone.0001987
PMCID: PMC2288678

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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