Article
Identification and characterization of single nucleotide polymorphisms of SLC22A11 (hOAT4) in Korean women osteoporosis patients.
Molecules and cells - 30 Apr 2008
Lee Woon Kyu, Kwak Jin Oh, Hwang Ji-Sun, Suh Chang Kook, Cha Seok Ho
Abstract excerpt
Single nucleotide polymorphisms (SNPs) are the most common form of human genetic variation. Non-synonymous SNPs (nsSNPs) change an amino acid. Organic anion transporters (OATs) play an important role in eliminating or reabsorbing endogenous and exogenous organic anionic compounds. Among OATs, hOAT4 mediates high affinity transport of estrone sulfate and dehydroepiandrosterone sulfate. The rapid bone loss that...
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