Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rare genetic variants in the sodium-dependent organic anion transporter SOAT (SLC10A6): Effects on transport function and membrane expression.

The Journal of steroid biochemistry and molecular biology - 1 May 2018

Bennien Josefine, Fischer Thomas, Geyer Joachim

Abstract excerpt

Sulfo-conjugated steroid hormones, such as dehydroepiandrosterone sulfate (DHEAS), pregnenolone sulfate or estrone-3-sulfate are abundant in the body, but are biologically inactive at classical androgen and estrogen steroid receptors. However, after carrier-mediated import and de-conjugation by the steroid sulfatase, these compounds participate in the overall steroid regulation of reproductive organs. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Transport
Share to Dehydroepiandrosterone Sulfate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HEK293 Cells

Share to Organic Anion Transporters

Share to Organic Anion Transporters, Sodium-Dependent

Share to Sodium

Share to Structural Homology, Protein

Share to Symporters

Source

Identifiers

PMID: 28893621
DOI: 10.1016/j.jsbmb.2017.09.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rare genetic variants in the sodium-dependent organic anion transporter SOAT (SLC10A6): Effects on transport function and membrane expression.PMID 28893621Read ↗

The polymorphism L204F affects transport and membrane expression of the sodium-dependent organic anion transporter SOAT (SLC10A6).Semantic proximity Read ↗

MBOAT1 homozygous missense variant causes nonobstructive azoospermia.Semantic proximity Read ↗

Homozygous p.Ser267Phe in SLC10A1 is associated with a new type of hypercholanemia and implications for personalized medicine.Semantic proximity Read ↗

Functional Characterization Reveals the Significance of Rare Coding Variations in Human Organic Anion Transporting Polypeptide 2B1 (SLCO2B1).Semantic proximity Read ↗

Identification and characterization of single nucleotide polymorphisms of SLC22A11 (hOAT4) in Korean women osteoporosis patients.Semantic proximity Read ↗

Type 1 sodium-dependent phosphate transporter acts as a membrane potential-driven urate exporter.Semantic proximity Read ↗

Genetic variants in Ser-Arg protein-coding genes are associated with the risk of nonobstructive azoospermia in Chinese men.Semantic proximity Read ↗

Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studiesSemantic proximity Read ↗

The human organic anion transporter 3 (OAT3; SLC22A8): genetic variation and functional genomics.Semantic proximity Read ↗

Genetic polymorphisms of human organic anion transporters OATP-C (SLC21A6) and OATP-B (SLC21A9): allele frequencies in the Japanese population and functional analysis.Semantic proximity Read ↗

Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studiesSemantic proximity Read ↗

Missense mutations in SLC26A8, encoding a sperm-specific activator of CFTR, are associated with human asthenozoospermia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.