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Article

Functional consequences of single nucleotide polymorphisms in the human organic anion transporter hOAT1 (SLC22A6).

The Journal of pharmacology and experimental therapeutics - 1 Aug 2005

Bleasby Kelly, Hall Laura A, Perry Jennifer L, Mohrenweiser Harvey W, Pritchard John B

Abstract excerpt

The human organic anion transporter hOAT1 (SLC22A6) contributes to the uptake of a range of small organic anions across the basolateral membrane of the renal proximal tubule and drives their urinary elimination. The aim of this study was to identify genetic variants of hOAT1 and to investigate potential effects on the functional properties of this transporter. Twenty single nucleotide polymorphisms (SNPs) in...

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PMID: 15914676
DOI: 10.1124/jpet.105.084301

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PAH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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