Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional characterization of human organic cation transporter OCTN1 single nucleotide polymorphisms in the Japanese population.

Journal of pharmaceutical sciences - 1 Dec 2004

Kawasaki Yuki, Kato Yukio, Sai Yoshimichi, Tsuji Akira

Abstract excerpt

The organic cation transporter OCTN1 (SLC22A4) is expressed ubiquitously, with strong expression in kidney, trachea, bone marrow, and fetal liver, and it mediates transport of organic cations in a pH-dependent manner. Recent studies have identified single nucleotide polymorphisms (SNPs) of OCTN1 in the Japanese population. Two SNPs present in the exon regions, c1063t and g1531a, cause amino acid mutation,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Cell Line
Share to Gene Expression Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Membrane Transport Proteins

Share to Organic Cation Transport Proteins

Share to Polymorphism, Single Nucleotide

Share to Substrate Specificity

Share to Symporters

Source

Identifiers

PMID: 15459889
DOI: 10.1002/jps.20190

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional characterization of human organic cation transporter OCTN1 single nucleotide polymorphisms in the Japanese population.PMID 15459889Read ↗

Novel single nucleotide polymorphisms of organic cation transporter 1 (SLC22A1) affecting transport functions.Semantic proximity Read ↗

Functional effects of protein sequence polymorphisms in the organic cation/ergothioneine transporter OCTN1 (SLC22A4)Semantic proximity Read ↗

Seven novel single nucleotide polymorphisms in the human SLC22A1 gene encoding organic cation transporter 1 (OCT1).Semantic proximity Read ↗

The human organic cation transporter OCT1 and its role as a target for drug responsesSemantic proximity Read ↗

Genetic polymorphisms in organic cation transporter 1 (OCT1) in Chinese and Japanese populations exhibit altered function.Semantic proximity Read ↗

cDNA Sequence, Transport Function, and Genomic Organization of Human OCTN2, a New Member of the Organic Cation Transporter FamilySemantic proximity Read ↗

The Impact of Genetic Polymorphisms in Organic Cation Transporters on Renal Drug DispositionSemantic proximity Read ↗

Identification and functional characterization of novel nonsynonymous variants in the human multidrug and toxin extrusion 2-K.Semantic proximity Read ↗

Organic cation transporters.Semantic proximity Read ↗

Functional analysis of human organic cation transporter OCT3 (SLC22A3) polymorphisms.Semantic proximity Read ↗

Functional characterization of nonsynonymous single nucleotide polymorphisms in the electrogenic Na+-HCO3- cotransporter NBCe1A.Semantic proximity Read ↗

Organic cation transporters.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.