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Article

Molecular analysis of metaplastic breast carcinoma: high EGFR copy number via aneusomy.

Molecular cancer therapeutics - 1 Apr 2008

Gilbert Judith A, Goetz Matthew P, Reynolds Carol A, Ingle James N, Giordano Karin F, Suman Vera J, Blair Hilary E, Jenkins Robert B, Lingle Wilma L, Reinholz Monica M, Adjei Alex A, Ames Matthew M

Abstract excerpt

Metaplastic breast carcinoma, a rare tumor composed of adenocarcinomatous and nonglandular growth patterns, is characterized by a propensity for distant metastases and resistance to standard anticancer therapies. We sought confirmation that this tumor is a basal-like breast cancer, expressing epidermal growth factor receptor (EGFR) and stem cell factor receptor (KIT). EGFR activating mutations and high copy...

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Share to Aneuploidy
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18413808
DOI: 10.1158/1535-7163.MCT-07-0570
PMCID: PMC2745608

Genes

EGFR
KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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