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Protein expression, gene amplification, and mutational analysis of EGFR in triple-negative breast cancer.

Breast cancer (Tokyo, Japan) - 1 Jan 2014

Nakajima Hiroki, Ishikawa Yuko, Furuya Mio, Sano Takaaki, Ohno Yoshihiro, Horiguchi Jun, Oyama Tetsunari

Abstract excerpt

BACKGROUND: Although triple-negative breast cancer (TNBC) with epidermal growth factor receptor (EGFR) expression has been extensively studied, few studies have simultaneously examined EGFR expression and EGFR gene amplification. Here, we examined the correlations of EGFR expression with EGFR gene amplification, EGFR-activating mutations, and the expression of components of the Akt pathway. METHODS: Tumor tissues...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 7

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Identifiers

PMID: 22481575
DOI: 10.1007/s12282-012-0354-1

Genes

EGFR

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