Article
Association of the G protein beta3 subunit T allele with insulin resistance in essential hypertension.
Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Jul 2002
Poch Esteban, Giner Vicente, González-Núñez Daniel, Coll Elisabeth, Oriola Josep, de la Sierra Alejandro
Abstract excerpt
A polymorphism (C825T) in the gene encoding the G protein beta3 subunit (GNB3) has recently been associated with hypertension and obesity in several populations. The aim of the study was to analyse the relationship between this polymorphism and insulin sensitivity, an hypothesised unifying factor for hypertension and obesity. One hundred thirty unrelated patients with essential hypertension, 70 female and 60...
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