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Article

Association of endothelial nitric oxide synthase Glu298Asp polymorphism with end-stage renal disease.

Clinical nephrology - 1 Aug 2008

Thaha M, Pranawa, Yogiantoro M, Sutjipto, Sunarjo, Tanimoto M, Gohda T, Tomino Y

Abstract excerpt

BACKGROUND: Impairment of nitric oxide generation caused by gene polymorphism is considered as a major factor in the deterioration of progressive renal disease, including diabetic nephropathy and hypertension. The aim of the present study was to examine the Glu298Asp polymorphism of endothelial nitric oxide synthase (eNOS) in patients with end-stage renal disease (ESRD). METHODS: The Glu298Asp polymorphism in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18793530
DOI: 10.5414/cnp70144

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