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Article

The Legionella autoinducer synthase LqsA produces an alpha-hydroxyketone signaling molecule.

The Journal of biological chemistry - 27 Jun 2008

Spirig Thomas, Tiaden André, Kiefer Patrick, Buchrieser Carmen, Vorholt Julia A, Hilbi Hubert

Abstract excerpt

The opportunistic pathogen Legionella pneumophila replicates in human lung macrophages and in free-living amoebae. To accommodate the transfer between host cells, L. pneumophila switches from a replicative to a transmissive phase. L. pneumophila harbors a gene cluster homologous to the Vibrio cholerae cqsAS quorum sensing system, encoding a putative autoinducer synthase (lqsA) and a sensor kinase (lqsS), which...

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Share to Gene Expression Regulation, Bacterial
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18411263
DOI: 10.1074/jbc.M801929200
PMCID: PMC2440625

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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