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Article

Mutations in String/CDC25 inhibit cell cycle re-entry and neurodegeneration in a Drosophila model of Ataxia telangiectasia.

Genes & development - 1 May 2008

Rimkus Stacey A, Katzenberger Rebeccah J, Trinh Anthony T, Dodson Gerald E, Tibbetts Randal S, Wassarman David A

Abstract excerpt

Mutations in ATM (Ataxia telangiectasia mutated) result in Ataxia telangiectasia (A-T), a disorder characterized by progressive neurodegeneration. Despite advances in understanding how ATM signals cell cycle arrest, DNA repair, and apoptosis in response to DNA damage, it remains unclear why loss...

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Source

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Identifiers

PMID: 18408079
DOI: 10.1101/gad.1639608
PMCID: PMC2335316

Genes

ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18408079-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Mutations in String/CDC25 inhibit cell cycle re-entry and neurodegeneration in a Drosophila model of Ataxia telangiectasia.PMID 18408079Read ↗

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ATM: genome stability, neuronal development, and cancer cross paths.Semantic proximity Read ↗

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