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Article

Ataxia-telangiectasia and related diseases.

Neuromolecular medicine - 1 Jan 2006

Frappart Pierre-Olivier, McKinnon Peter J

Abstract excerpt

Appropriate cellular signaling responses to DNA damage and the ability to repair DNA are fundamental processes that are required for organismal survival. Ataxia-telangiectasia (A-T) is a rare neurodegenerative disease that results from defective DNA damage signaling. Understanding the molecular basis of A-T has provided many critical insights into the cellular response to DNA double-strand breaks (DSBs). A-T is a...

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Identifiers

PMID: 17028372
DOI: 10.1385/NMM:8:4:495

Genes

ATM
RAD50

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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