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Article

A nervous predisposition to unrepaired DNA double strand breaks.

DNA repair - 1 Aug 2013

Reynolds John J, Stewart Grant S

Abstract excerpt

Ataxia-telangiectasia (A-T) has for a long time stood apart from most other human neurodegenerative syndromes by the characteristic failure of cells derived from these patients to properly repair DNA damage-induced by ionizing radiation. The discovery of mutations in the ATM gene as being the underlying cause for A-T and the demonstration that the ATM protein functions as a DNA damage-responsive kinase has...

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Source

Identifiers

PMID: 23684796
DOI: 10.1016/j.dnarep.2013.04.011

Genes

ATM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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