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Article

The hepatitis B virus S promoter comprises A CCAAT motif and two initiation regions.

The Journal of biological chemistry - 5 Dec 1991

Zhou D X, Yen T S

Abstract excerpt

The hepatitis B virus S (major surface gene) promoter is embedded in two overlapping open reading frames and specifies several transcripts with heterogeneous 5' termini. We have identified the cis-elements necessary for S promoter function. A single upstream CCAAT element is essential for high level expression in both liver and non-liver cells. No TATA box is present, but two regions surrounding the initiation...

Topics

Base Sequence
DNA, Viral
Hepatitis B Surface Antigens
Hepatitis B virus
Molecular Sequence Data
Mutation
Promoter Regions, Genetic
Regulatory Sequences, Nucleic Acid
Transcription, Genetic

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1840596

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1840596-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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