Article
The TATA-less promoter of hepatitis B virus S gene contains a TBP binding site and an active initiator.
Virus research - 1 May 1997
Bogomolski-Yahalom V, Klein A, Greenblat I, Haviv Y, Tur-Kaspa R
Abstract excerpt
The surface antigen (S) gene promoter, one of the major hepatitis B virus (HBV) promoters, directs the synthesis of a 2.1 kb mRNA which encodes the preS2 and S polypeptides. The preS2/S promoter does not contain a classical TATA box, and transcription regulation of the preS2/S gene has not been f...
Topics
- Base Sequence
- Binding Sites
- Carcinoma, Hepatocellular
- Chloramphenicol O-Acetyltransferase
- Cloning, Molecular
- DNA, Viral
- DNA-Binding Proteins
- Genetic Variation
- Hepatitis B Surface Antigens
- Hepatitis B virus
- Humans
- Liver Neoplasms
- Molecular Sequence Data
- Promoter Regions, Genetic
- Recombinant Fusion Proteins
- Recombinant Proteins
- TATA Box
- TATA-Box Binding Protein