Article
Multiple liver-specific factors bind to the hepatitis B virus core/pregenomic promoter: trans-activation and repression by CCAAT/enhancer binding protein.
Proceedings of the National Academy of Sciences of the United States of America - 1 Jul 1990
López-Cabrera M, Letovsky J, Hu K Q, Siddiqui A
Abstract excerpt
The human hepatitis B virus (HBV) is a hepatotropic virus that replicates through an RNA intermediate referred to as the pregenome. The promoter that directs the synthesis of the pregenome and several other transcripts with heterogeneous 5' ends is of particular interest because of its role in re...
Topics
- Animals
- Base Sequence
- Binding Sites
- CCAAT-Enhancer-Binding Proteins
- Cell Line
- Cell Nucleus
- Chromosome Deletion
- DNA-Binding Proteins
- Deoxyribonuclease I
- Genes, Viral
- HeLa Cells
- Hepatitis B virus
- Humans
- Liver
- Molecular Sequence Data