Article
Expression of estrogen receptor beta in the breast carcinoma of BRCA1 mutation carriers.
BMC cancer - 13 Apr 2008
Litwiniuk Maria M, Roznowski Krzysztof, Filas Violetta, Godlewski Dariusz D, Stawicka Małgorzata, Kaleta Remigiusz, Breborowicz Jan
Abstract excerpt
BACKGROUND: Breast cancers (BC) in women carrying mutations in BRCA1 gene are more frequently estrogen receptor negative than the nonhereditary BC. Nevertheless, tamoxifen has been found to have a protective effect in preventing contralateral tumors in BRCA1 mutation carriers. The identification of the second human estrogen receptor, ERbeta, raised a question of its role in hereditary breast cancer. The aim of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
