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Article

Androgen pathway dysregulation in BRCA1-mutated breast tumors.

Breast cancer research and treatment - 1 May 2003

Berns Els M J J, Dirkzwager-Kiel Maaike J M, Kuenen-Boumeester Vibeke, Timmermans Mieke, Verhoog Leon C, van den Ouweland Ans M W, Meijer-Heijboer Hanne, Klijn Jan G M, van der Kwast Theo H

Abstract excerpt

BACKGROUND: Using array analysis for screening RNA from BRCA1-mutated and sporadic breast tumors, we observed that AIGF/FGF-8 expression was lost in BRCA1-mutated breast tumors. Since this growth factor is induced by androgens, we studied the androgen receptor (AR) expression in BRCA-mutated tumo...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12779088
DOI: 10.1023/a:1023347409599

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12779088-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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