Article
Monochromosome transfer and microarray analysis identify a critical tumor-suppressive region mapping to chromosome 13q14 and THSD1 in esophageal carcinoma.
Molecular cancer research : MCR - 1 Apr 2008
Ko Josephine M Y, Chan Pui Ling, Yau Wing Lung, Chan Ho Kin, Chan King Chi, Yu Zhuo You, Kwong Fung Mei, Miller Lance D, Liu Edison T, Yang Li Chun, Lo Paulisally H Y, Stanbridge Eric J, Tang Johnny C O, Srivastava Gopesh, Tsao Sai Wah, Law Simon, Lung Maria L
Abstract excerpt
Loss of chromosome 13q regions in esophageal squamous cell carcinoma (ESCC) is a frequent event. Monochromosome transfer approaches provide direct functional evidence for tumor suppression by chromosome 13 in SLMT-1, an ESCC cell line, and identify critical regions at 13q12.3, 13q14.11, and 13q14...
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