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Article

Dysregulation of CXCL14 promotes malignant phenotypes of esophageal squamous carcinoma cells via regulating SRC and EGFR signaling.

Biochemical and biophysical research communications - 18 Jun 2022

Guo Jing, Chang Chen, Yang Li-Yan, Cai Hong-Qing, Chen Ding-Xiong, Zhang Yu, Cai Yan, Wang Juan-Juan, Wei Wen-Qiang, Hao Jia-Jie, Wang Ming-Rong

Abstract excerpt

The present study was to identify abnormal methylation genes implicated in esophageal squamous cell carcinoma (ESCC). Genomic methylation alterations in ESCC tissues were analyzed using laser-microdissection and whole-genome bisulfite sequencing. CXCL14 promoter was frequently hypermethylated in ESCC tissues. The correlation of CXCL14 hypermethylation status and the mRNA and protein expression levels were...

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Identifiers

PMID: 35421632
DOI: 10.1016/j.bbrc.2022.03.144

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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