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Article

DIF-1 induces the basal disc of the Dictyostelium fruiting body.

Developmental biology - 15 May 2008

Saito Tamao, Kato Atsushi, Kay Robert R

Abstract excerpt

The polyketide DIF-1 induces Dictyostelium amoebae to form stalk cells in culture. To better define its role in normal development, we examined the phenotype of a mutant blocking the first step of DIF-1 synthesis, which lacks both DIF-1 and its biosynthetic intermediate, dM-DIF-1 (des-methyl-DIF-1). Slugs of this polyketide synthase mutant (stlB(-)) are long and thin and rapidly break up, leaving an immotile...

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Identifiers

PMID: 18402932
DOI: 10.1016/j.ydbio.2008.02.036
PMCID: PMC2726288

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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DIF-1 induces the basal disc of the Dictyostelium fruiting body.PMID 18402932Read ↗

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