Article
A new bone to pick: osteoblasts and the haematopoietic stem-cell niche.
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Jun 2004
Zhu Jiang, Emerson Stephen G
Abstract excerpt
Two recent publications highlight the role of bone-forming cells, the osteoblasts, in controlling the development of neighboring haematopoietic stem cells (HSCs).1,2 Using two distinct transgenic mouse models, one using the conditional deletion of the Bone Morphogenetic Protein Receptor 1A (BMPR1A) gene, the other using over-expression of an active PTH/PTHrP receptor (PPR) mutant within osteoblasts, the authors...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
