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Article

The stem cell niches in bone

1 May 2006

Abstract excerpt

The stem cell niche is composed of a specialized population of cells that plays an essential role in regulating adult stem cell self-renewal and differentiation. In adults, osteoblasts, responsible for osteogenesis, and hematopoietic cells, responsible for hematopoiesis, are closely associated in the bone marrow, suggesting a reciprocal relationship between the two. It was recently discovered that a subset of...

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PMID: 16670760
DOI: 10.1172/jci28568

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