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Article

Genome-wide analysis identifies 16q deletion associated with survival, molecular subtypes, mRNA expression, and germline haplotypes in breast cancer patients.

Genes, chromosomes & cancer - 1 Aug 2008

Nordgard Silje H, Johansen Fredrik E, Alnaes Grethe I G, Bucher Elmar, Syvänen Ann-Christine, Naume Bjørn, Børresen-Dale Anne-Lise, Kristensen Vessela N

Abstract excerpt

Breast carcinomas are characterized by DNA copy number alterations (CNAs) with biological and clinical significance. This explorative study integrated CNA, expression, and germline genotype data of 112 early-stage breast cancer patients. Recurrent CNAs differed substantially between tumor subtypes classified according to expression pattern. Deletion of 16q was overrepresented in Luminal A, and a predictor of good...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Chromosomes, Human, Pair 16

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Source

Identifiers

PMID: 18398821
DOI: 10.1002/gcc.20569

Genes

ADAMTS18
CHST3
CNTNAP4
KPNB1
PTPRN2
SPOCK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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