Article
The CD85j+ NK cell subset potently controls HIV-1 replication in autologous dendritic cells.
PloS one - 9 Apr 2008
Scott-Algara Daniel, Arnold Vincent, Didier Céline, Kattan Tarek, Pirozzi Gianluca, Barré-Sinoussi Françoise, Pancino Gianfranco
Abstract excerpt
Natural killer (NK) cells and dendritic cells (DC) are thought to play critical roles in the first phases of HIV infection. In this study, we examined changes in the NK cell repertoire and functions occurring in response to early interaction with HIV-infected DC, using an autologous in vitro NK/DC coculture system. We show that NK cell interaction with HIV-1-infected autologous monocyte-derived DC (MDDC)...
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