Article
In vitro infection of natural killer cells with different human immunodeficiency virus type 1 isolates.
Journal of virology - 1 Apr 1991
Chehimi J, Bandyopadhyay S, Prakash K, Perussia B, Hassan N F, Kawashima H, Campbell D, Kornbluth J, Starr S E
Abstract excerpt
Natural killer (NK) cells are a discrete subset of leukocytes, distinct from T and B lymphocytes. NK cells mediate spontaneous non-MHC-restricted killing of a wide variety of target cells without prior sensitization and appear to be involved in initial protection against certain viral infections. Depressed NK cell-mediated cytotoxicity, one of the many immunological defects observed in AIDS patients, may...
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