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Prohibitin 3' untranslated region polymorphism and breast cancer risk in Australian women.

Lancet (London, England) - 21 Sept 2002

Spurdle Amanda B, Hopper John L, Chen Xiaoqing, McCredie Margaret R E, Giles Graham G, Newman Beth, Chenevix-Trench Georgia

Abstract excerpt

A C to T transition within the 3' untranslated region of the prohibitin gene alters mRNA function, and an association between the T allele and an increased risk of breast cancer has been reported in North American women, specifically in those aged under 50 years with a first-degree family history...

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Identifiers

PMID: 12354477
DOI: 10.1016/S0140-6736(02)11043-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12354477-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Prohibitin 3' untranslated region polymorphism and breast cancer risk in Australian women.PMID 12354477Read ↗

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Relationship between the prohibitin 3' untranslated region C > T gene polymorphism and cancer susceptibility--results of a meta-analysis.Semantic proximity Read ↗

The 3' untranslated region C > T polymorphism of prohibitin is a breast cancer risk modifier in Polish women carrying a BRCA1 mutation.Semantic proximity Read ↗

The prohibitin 3' untranslated region polymorphism in patients with ovarian cancer.Semantic proximity Read ↗

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No evidence for association of ataxia-telangiectasia mutated gene T2119C and C3161G amino acid substitution variants with risk of breast cancer.Semantic proximity Read ↗

Prohibitin in breast cancer cell lines: loss of antiproliferative activity is linked to 3' untranslated region mutations.Semantic proximity Read ↗

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The steroid 5alpha-reductase type II TA repeat polymorphism is not associated with risk of breast or ovarian cancer in Australian women.Semantic proximity Read ↗

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