Article
The presence of DRB1*01 allele in multiple myeloma patients is associated with an indolent disease.
Tissue antigens - 1 Jun 2008
Alcoceba M, Marín L, Balanzategui A, Sarasquete M E, Martín-Jiménez P, Chillón M C, Corral R, Pérez-Persona E, Fernández-Calvo F J, Hernández J M, Bladé J, Lahuerta J J, González M, San Miguel J F, García-Sanz R
Abstract excerpt
The human leukocyte antigen (HLA) system could play an essential role in multiple myeloma (MM) disease control. This report describes the results comparing HLA-DRB1 phenotypic frequencies in 181 MM patients (53 smoldering/indolent MM and 128 symptomatic MM patients) and healthy individuals. Higher DRB1*01 phenotypic frequencies were found in the smoldering patients compared with symptomatic MM patients (38% vs...
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