Article

Patients with Multiple Myeloma Have Increased Co-Expression of HLA-E and HLA-DR Molecules on T-Lymphocytes and Monocytes in Peripheral Blood

2025-12-30

Abstract excerpt

<h4>Background: </h4> /Objectives: Multiple myeloma (MM) is characterized by complex interactions between tumor plasma cells and the tumor microenvironment, in which immune escape mechanisms play a key role. Non-classical major histocompatibility complex (MHC) molecules HLA-E and HLA-G are receptors capable of suppressing the activity of NK cells and T lymphocytes. However, their expression on immune cells in onco...

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Literature Corpus work: 5a300f7a-cd91-5ea1-8468-c948c32aa113
DOI: 10.20944/preprints202512.2630.v1

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