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Article

TLR4/TIRAP polymorphisms are associated with progression and survival of patients with symptomatic myeloma.

British journal of haematology - 1 Jan 2016

Bagratuni Tina, Terpos Evangelos, Eleutherakis-Papaiakovou Evangelos, Kalapanida Despoina, Gavriatopoulou Maria, Migkou Magdalini, Liacos Christine-Ivy, Tasidou Anna, Matsouka Charis, Mparmparousi Despoina, Dimopoulos Meletios A, Kastritis Efstathios

Abstract excerpt

Myeloma cells thrive in an environment of sustained inflammation, which impacts the development and evolution of the disease, as well as drug resistance. We evaluated the impact of genetic polymorphisms in the Toll-like receptor 4 (TLR4) pathway, which have been implicated in different inflammatory responses in the outcomes of patients with symptomatic multiple myeloma (MM) who have received contemporary...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26564000
DOI: 10.1111/bjh.13786

Genes

TIRAP
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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