Article
Interleukin-1 gene complex single nucleotide polymorphisms in systemic sclerosis: a further step ahead.
Human immunology - 1 Mar 2008
Beretta Lorenzo, Cappiello Francesca, Moore Jason H, Scorza Raffaella
Abstract excerpt
Gene-gene and gene-environment interactions are difficult to detect by traditional parametric computational approaches. Novel nonparametric and model-free strategies, such as the multifactor dimensionality reduction (MDR) algorithm, are thus emerging as practical and feasible methods of analysis to model high-order epistatic interactions, integrating and complementing traditional logistic approaches. With...
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