Article
Cytokine genes multi-locus analysis reveals synergistic influence on genetic susceptibility in Indian SLE - A multifactor-dimensionality reduction approach.
Cytokine - 1 Nov 2020
Umare Vinod, Pradhan Vandana, Dadheech Sneha, Rajadhyaksha Anjali, Ghosh Kanjaksha, Nadkarni Anita
Abstract excerpt
Systemic lupus erythematosus (SLE) is a prototype autoimmune disease with unclear etiology. Several loci associated with genetic susceptibility for lupus have been described. However, it lacks reports on cytokine gene-gene interactions among SLE patients from Asian population. Epistasis interaction among single nucleotide polymorphisms (SNPs) of cytokine genes in Indian SLE patients was tested using...
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