Article
Statistical resolution of ambiguous HLA typing data.
PLoS computational biology - 29 Feb 2008
Listgarten Jennifer, Brumme Zabrina, Kadie Carl, Xiaojiang Gao, Walker Bruce, Carrington Mary, Goulder Philip, Heckerman David
Abstract excerpt
High-resolution HLA typing plays a central role in many areas of immunology, such as in identifying immunogenetic risk factors for disease, in studying how the genomes of pathogens evolve in response to immune selection pressures, and also in vaccine design, where identification of HLA-restricted epitopes may be used to guide the selection of vaccine immunogens. Perhaps one of the most immediate applications is...
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