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Article

MDM2 and p53 polymorphisms are associated with the development of hepatocellular carcinoma in patients with chronic hepatitis B virus infection.

Carcinogenesis - 1 Jun 2008

Yoon Young Joon, Chang Hye Young, Ahn Sang Hoon, Kim Ja Kyung, Park Yong Kwang, Kang Dae Ryong, Park Jun Yong, Myoung Sung Min, Kim Do Young, Chon Chae Yoon, Han Kwang-Hyub

Abstract excerpt

A single-nucleotide polymorphism (SNP) in the promoter region of MDM2, SNP 309, is associated with hepatocellular carcinoma (HCC) in patients with chronic hepatitis C virus infection. The effect of p53 codon 72 polymorphism Arg72Pro on HCC risk remains inconsistent. This study evaluated the association of MDM2 and p53 polymorphisms with the presence and early onset of HCC in Korean patients with chronic hepatitis...

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Share to Age of Onset
Share to Carcinoma, Hepatocellular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, p53

Share to Hepatitis B, Chronic

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Share to Proto-Oncogene Proteins c-mdm2

Source

Identifiers

PMID: 18390844
DOI: 10.1093/carcin/bgn090

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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MDM2 and p53 polymorphisms are associated with the development of hepatocellular carcinoma in patients with chronic hepatitis B virus infection.PMID 18390844Read ↗

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