Article
LET-767 is required for the production of branched chain and long chain fatty acids in Caenorhabditis elegans.
The Journal of biological chemistry - 20 Jun 2008
Entchev Eugeni V, Schwudke Dominik, Zagoriy Vyacheslav, Matyash Vitali, Bogdanova Aliona, Habermann Bianca, Zhu Lin, Shevchenko Andrej, Kurzchalia Teymuras V
Abstract excerpt
LET-767 from Caenorhabditis elegans belongs to a family of short chain dehydrogenases/reductases and is homologous to 17beta-hydroxysterol dehydrogenases of type 3 and 3-ketoacyl-CoA reductases. Worms subjected to RNA interference (RNAi) of let-767 displayed multiple growth and developmental defects in the first generation and arrested in the second generation as L1 larvae. To determine the function of LET-767 in...
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