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Article

A novel sphingolipid-TORC1 pathway critically promotes postembryonic development in Caenorhabditis elegans.

eLife - 21 May 2013

Zhu Huanhu, Shen Huali, Sewell Aileen K, Kniazeva Marina, Han Min

Abstract excerpt

Regulation of animal development in response to nutritional cues is an intensely studied problem related to disease and aging. While extensive studies indicated roles of the Target of Rapamycin (TOR) in sensing certain nutrients for controlling growth and metabolism, the roles of fatty acids and lipids in TOR-involved nutrient/food responses are obscure. Caenorhabditis elegans halts postembryonic growth and...

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Identifiers

PMID: 23705068
DOI: 10.7554/eLife.00429
PMCID: PMC3660743

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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