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Exon 33 T/T genotype of the thyroglobulin gene is a susceptibility gene for Graves' disease in Taiwanese and exon 12 C/C genotype protects against it.

Clinical and experimental medicine - 1 Mar 2008

Hsiao Jeng-Yueh, Hsieh Ming-Chia, Tien Kai-Jen, Hsu Shih-Chie, Lin Shiu-Ru, Ke Der-Shin

Abstract excerpt

This study investigates whether Tg gene polymorphisms can be associated with Graves' disease (GD) in a Taiwanese population and identifies potential polygenic susceptive genes for GD. The findings of such a study may have important implications for prognostic prediction and treatment of GD. We performed case control association studies for the 3 discovered Tg single nucleotide polymorphisms (SNPs) (E10, E12, E33)...

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Identifiers

PMID: 18385936
DOI: 10.1007/s10238-008-0151-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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