Article
HLA class I and II gene polymorphisms in Stevens-Johnson syndrome with ocular complications in Japanese.
Molecular vision - 17 Mar 2008
Ueta Mayumi, Tokunaga Katsushi, Sotozono Chie, Inatomi Tsutomu, Yabe Toshio, Matsushita Masaki, Mitsuishi Yoko, Kinoshita Shigeru
Abstract excerpt
PURPOSE: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are acute-onset mucocutaneous diseases induced by infectious agents and/or inciting drugs. Although the pathobiological mechanisms underlying the onset of SJS/TEN have not been fully established, the extreme rarity of cutaneous and ocular surface reactions to drug therapies led us to suspect individual susceptibility. Our previous study...
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