HLA typing in patients with ocular manifestations of Stevens-Johnson syndrome.

doi:10.1016/s0161-6420(96)30491-0

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Article

HLA typing in patients with ocular manifestations of Stevens-Johnson syndrome.

Ophthalmology - 1 Sept 1996

Power W J, Saidman S L, Zhang D S, Vamvakas E C, Merayo-Lloves J M, Kaufman A H, Foster C S

Abstract excerpt

BACKGROUND: Stevens-Johnson syndrome (SJS) is an acute, self-limited, inflammatory disorder of the skin and mucous membranes. With ocular involvement, SJS has been associated with the class I human leukocyte antigen (HLA)-Bw44. This study examined HLA class II associations in patients with SJS wi...

Topics

Adult
Alleles
DNA
Eye Diseases
Female
Gene Frequency
Genes, MHC Class II
Genotype
HLA-DQ Antigens
HLA-DR Antigens
Histocompatibility Testing
Humans
Male
Polymerase Chain Reaction
Risk Factors
Stevens-Johnson Syndrome

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