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Article

Human leukocyte antigen-G 3' untranslated region polymorphisms are associated with asthma severity.

Molecular immunology - 1 Sept 2018

Alves Cinthia C, Arruda Luísa K P, Oliveira Fabíola R, Massaro Juliana D, Aquino Beatriz J, Paz Michelle A, Castelli Erick C, Mendes-Junior Celso T, Donadi Eduardo A

Abstract excerpt

Asthma is a genetically complex chronic inflammatory airway disorder, and according to disease pathogenesis, clinical manifestations may vary according to asthma severity. A gene region close to the human leukocyte antigen-G (HLA-G) gene was identified as an independent susceptibility marker for asthma. Considering that the HLA-G immune checkpoint molecule may modulate inflammation, we evaluated the diversity of...

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PMID: 30142579
DOI: 10.1016/j.molimm.2018.08.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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