Article
Functional single nucleotide polymorphisms of the CCL5 gene and nonemphysematous phenotype in COPD patients.
The European respiratory journal - 1 Aug 2008
Hizawa N, Makita H, Nasuhara Y, Hasegawa M, Nagai K, Ito Y, Betsuyaku T, Konno S, Nishimura M
Abstract excerpt
It was previously reported that the gain-of-function -28 guanine allele of the promoter single nucleotide polymorphism (SNP; cytosine to guanine substitution of nucleotide -28 (-28C>G)) in the CC chemokine ligand 5 gene (CCL5) was associated with susceptibility to late-onset asthma in patients wh...
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